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Aerial view of UCSD campus looking South

Geisel Library - Nobel Laureates at UCSD

Discovery of new atmospheric reaction garners prize

Urey Hall Addition

Pacific Hall

Natural Sciences Building

The crystal structure of a group II intron in the pre-catalytic state

Geisel Library Walk

York Hall

Structure of an inhibitor of hepatitis C virus protein synthesis bound to its target in the viral ribonucleic acid (RNA) genome

ANCA probe staining amyloid plaques derived from Alzheimer’s-related Aβ peptides fluoresces as green and as yellow when derived from prion proteins (PrPSC)

Price Center

Generation of bio-resistive surface coatings on amyloids inhibits harmful protein-amyloid interactions associated with Alzheimer disease

Proposed schematic models of the interfacial binding surface of four different members of the Phospholipase A2 superfamily

Urey Hall and Pacific Hall

Characterization of the "inhibitor binding pocket" in the catalytic domain of the calcium-independent phospholipase A2 with residues within a 5 A raidus of the inhibitor shown

A Crystalline Singlet Phosphinonitrene: a Nitrogen Atom Transfer Agent

Mayer Hall

Drug candidate in orange envelope bound to UPPS

Possible binding modes for phospholipase A2 via its membrane interaction site, another allosteric site, and its catalytic site



News

UC Symposium for Chemical Sciences Poster Prize Recipient - Allie Chen
Congratulations to Allie Chen (Cohen Lab) on receiving the University of California Symposium for Chemical Sciences Dalton Transactions poster prize! The Symposium brought graduate students and postdocs from across the University of California together to network and star up new collaborations.

Dr. Lindenberg Awarded the Oliver Johnson Award for Distinguished Leadership in the Academic Senate!
It is our pleasure to inform you that Katja Lindenberg has been awarded the Oliver Johnson Award for Distinguished Leadership in the Academic Senate.

First SoCal Theoretical Chemistry Symposium
On June 4th, 2016 we will hold the very first Southern California Theoretical Chemistry (SoCal TheoChem) Symposium at the UC San Diego in La Jolla, CA. This one-day event will serve as a testimony of the vitality and high concentration of research groups engaged in theoretical chemistry in the geographical area. The primary goal of this boutique workshop is to provide a focused outlet for researchers to present their work to their colleagues, to network and build professional relationships, and to create a stronger community of researchers of the field in the region. The hope is that this workshop will be repeated in the future in different locations of Southern California.

Valerie Schmidt
Dr. Valerie Schmidt joins our organic division in the summer of 2016. She is currently a Postdoc at Princeton. Dr. Schmidt earned her PhD. from University of North Carolina-Chapel Hill in 2013.

Alina Schimpf
Dr. Alina Schimpf joins our inorganic division in the summer of 2016. She is currently a Postdoc at MIT. Dr. Schimpf earned her PhD. from the University of Washington in 2014.

Attention Undergrads: Apply for the 2016 Charles L. Perrin Undergrad Summer Fellowship APPLICATION
Attention Undergrads: Apply for the 2016 Charles L. Perrin Undergrad Summer Fellowship APPLICATION DEADLINE: May 1, 2016 AWARD AMOUNT: $1,000 PURPOSE: To support summer research with a Chemistry faculty member. MORE DETAILS: Contact Student Affairs, chemadvising@ucsd.edu

Congratulations to the 2016 Recipients of the NSF-GRFP!
We proudly announce that the National Science Foundation has selected Ember Tota from the Godula Lab and Jesse Peltier from the Bertrand Lab in the Department of Chemistry and Biochemistry as recipients of the 2016 Graduate Research Fellowship!

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Message from the Chair

Partho Ghosh, Chair



Faculty Spotlight

View profile for Albizati, Kim
Albizati, Kim

Chemical Education

View profile for Amaro, Rommie
Amaro, Rommie

Computational Chemistry and Biophysics

View profile for Baker, Timothy
Baker, Timothy

Macromolecular, cryoelectron microscopy and three-dimensional, image-reconstruction techniques.

View profile for Brydges, Stacey
Brydges, Stacey

Chemical Education: Development of context-rich curriculum; Use of collaborative learning strategies in large lectures; Communication of chemistry

View profile for Burkart, Michael
Burkart, Michael

Natural product synthesis/biosynthesis, Biological chemistry and enzymology, Metabolic engineering.

View profile for Bussey, Thomas
Bussey, Thomas

Chemical Education: Visual Literacy in Science, Biochemistry Education, Nano Science Education, K-20 Professional Development, and STEM Career Development

View profile for Cohen, Seth
Cohen, Seth

Bioinorganic and coordination chemistry. Metalloprotein inhibitors and supramolecular materials.

View profile for Continetti, Robert
Continetti, Robert

Dissociation dynamics of transient species, three-body reaction dynamics, novel mass-spectrometric methods

View profile for Crowell, John
Crowell, John

Materials chemistry, surface kinetics of metals/semiconductors, CVD, photo-induced deposition, thin-film spectroscopy.

View profile for Dennis, Edward
Dennis, Edward

Biochemistry: phospholipase A2, signal transduction in macrophages, lipid maps, prostaglandin regulation, mass spec of lipids and proteins.

View profile for Devaraj, Neal
Devaraj, Neal

Biomimetic Chemistry, Molecular Imaging, Chemical Biology

View profile for Dixon, Jack
Dixon, Jack

Protein Tyrosine Phosphatase, Dual=specific Phosphatase, PTEN

View profile for Donoghue, Daniel
Donoghue, Daniel

Fibroblast Growth Factor Receptors (FGFRs) in Human Cancer

View profile for Figueroa, Joshua
Figueroa, Joshua

Inorganic and Organometallic Chemistry: Synthesis, Small Molecule Activation and New Transformations.

View profile for Galperin, Michael
Galperin, Michael

Electron Transport in Condensed Phases. Dissipation and Relaxation Processes. Non-equilibrium Open Quantum Systems. Molecular Electronics.

View profile for Ghosh, Gourisankar
Ghosh, Gourisankar

Biochemistry and biophysics: transcription, signaling, pre-mRNA splicing, mRNA transport, protein-protein, protein-DNA and protein-RNA interactions

View profile for Ghosh, Partho
Ghosh, Partho

Mechanisms of bacterial and protozoan pathogenesis, and host response against infectious microbes.

View profile for Gianneschi, Nathan
Gianneschi, Nathan

Bioorganic chemistry, Supramolecular Chemistry, Bionanotechnology, Materials, Synthesis

View profile for Godula, Kamil
Godula, Kamil

Nanotechnologies for analysis of glycan function during development. Glycomaterials for stem cell-based tissue regeneration.

View profile for Grassian, Vicki
Grassian, Vicki

Surface science of complex environmental interfaces: heterogeneous atmospheric chemistry of sea spray and mineral dust; aerosol impacts on climate; applications and implications of nanoscience and nanotechnology in environmental processes and health.

View profile for Hermann, Thomas
Hermann, Thomas

RNA as a Drug Target.

View profile for Jennings, Patricia
Jennings, Patricia

Biophysical chemistry: protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies

View profile for Joseph, Simpson
Joseph, Simpson

Molecular Mechanism of Protein Synthesis

View profile for Kim, Judy
Kim, Judy

Biophysical chemistry: Spectroscopic studies of membrane protein folding and dynamics

View profile for Komives, Elizabeth
Komives, Elizabeth

Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics

View profile for Kubiak, Clifford
Kubiak, Clifford

Inorganic, materials, and physical chemistry: electron transfer, catalysis, fixation and utilization of carbon dioxide.

View profile for Kummel, Andrew
Kummel, Andrew

STM/STS of gate oxides on compound semiconductors and adsorbates on organic semiconductor

View profile for Lindenberg, Katja
Lindenberg, Katja

Theoretical chemical physics: non-equilibrium statistical mechanics; stochastic processes; nonlinear phenomena; complex systems; condensed matter.

View profile for McCammon, James
McCammon, James

Statistical mechanics and computational chemistry, with applications to biological systems

View profile for Molina, Mario
Molina, Mario

Physical Chemistry: Gas Phase Chemical Kinetics and Photochemistry; Chemistry of Atmospheric Aerosols; Air Pollution in Megacities of the Developing World

View profile for Molinski, Tadeusz
Molinski, Tadeusz

Organic chemistry of marine natural products, synthesis, NMR, and biomedical applications

View profile for Muller, Ulrich
Muller, Ulrich

Evolution of catalytic RNAs, and the Origin of Life

View profile for O'Connor, Joseph
O'Connor, Joseph

Organotransition metal; organic; physical organic; bioorganometallic; synthetic; and inorganic chemistry

View profile for Opella, Stanley
Opella, Stanley

NMR structural studies of proteins in membranes and other supramolecular assemblies

View profile for Paesani, Francesco
Paesani, Francesco

Theoretical chemical physics of complex interfaces of relevance to the environment

View profile for Perrin, Charles
Perrin, Charles

Physical-organic chemistry: stereoelectronic effects; hydrogen bonding; isotope effects; ionic solvation; naked anions; malonic anhydrides

View profile for Pomeroy, Robert
Pomeroy, Robert

The application of analytical chemistry to forensic, environmental and industrial chemistry, then bridge these experiences into the classroom. This also includes the role technology and instrumentation play in discovery and problem solving.

View profile for Prather, Kimberly
Prather, Kimberly

Environmental, physical/analytical chemistry: gas/particle processes of tropospheric significance; mass spectrometry; laser-based analysis techniques.

View profile for Rheingold, Arnold
Rheingold, Arnold

Inorganic chemistry: Small-molecule crystallography, synthesis of transition metal/p-block clusters

View profile for Rinehart, Jeffrey
Rinehart, Jeffrey

Inorganic, materials, and magnetochemistry

View profile for Sailor, Michael
Sailor, Michael

Nanomaterials: porous silicon, chemical and biological sensors, biomaterials, electrochemistry

View profile for Sawrey, Barbara
Sawrey, Barbara

Chemical education: development of computer-based multimedia to assist student learning of complex scientific processes and concepts

View profile for Sinha, Amitabha
Sinha, Amitabha

Experimental physical chemistry: photochemistry; laser spectroscopy; reaction dynamics of vibrationally excited molecules

View profile for Tauber, Michael
Tauber, Michael

Physical chemistry; Optical and magnetic spectroscopy; Fundamental studies of charge transport and solvation; Applications to energy conversion and energy storage.

View profile for Taylor, Susan
Taylor, Susan

Structure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase Superfamily.

View profile for Tezcan, Faik
Tezcan, Faik

Bioinorganic and biophysical chemistry; Metalloprotein structure, function and biosynthesis; Biomaterials

View profile for Theodorakis, Emmanuel
Theodorakis, Emmanuel

Synthetic, Medicinal, Bioorganic and Biological Chemistry, Methods and Strategies in Natural Products Chemistry

View profile for Thiemens, Mark
Thiemens, Mark

Atmospheric chemistry: physical chemistry of isotope effects; solar system formation

View profile for Toor, Navtej
Toor, Navtej

Structure and Function of Introns and Retroelements

View profile for Tor, Yitzhak
Tor, Yitzhak

Ligand-nucleic acid interactions; Antiviral and antibacterial agents; Fluorescent nucleosides and nucleotides; Cellular delivery vehicles

View profile for Trogler, William
Trogler, William

Inorganic chemistry: polymer chemistry; nanomaterials.

View profile for Tsien, Roger
Tsien, Roger

Chemical biology; design, synthesis, and application of molecular probes of biological function

View profile for Villa, Elizabeth
Villa, Elizabeth

Structural Cell Biology, Cryo-Electron Microscopy, Multiscale modeling

View profile for Wang, Wei
Wang, Wei

epigenomics, cellular reprogramming, protein recognition, computational biology, systems biology

View profile for Weare, John
Weare, John

Physical chemistry: calculations of the dynamics of complex systems; theoretical geochemistry

View profile for Weizman, Haim
Weizman, Haim

Chemical education, Bioorganic chemistry

View profile for Wollman, Roy
Wollman, Roy

Spatio-temporal signaling control of biological self-organization. Signaling networks in innate immunity. Microscopy; Mathematical modeling; Computational image analysis; Systems Biology.

View profile for Xiong, Wei
Xiong, Wei

Investigation of charge transfer mechanism in nanomaterials with novel ultrafast spectroscopies

View profile for Yang, Jerry
Yang, Jerry

Bioorganic Chemistry, Molecular Self-Assembly, Molecular Synthesis, Materials Chemistry, Bionanotechnology

View profile for Yuen Zhou, Joel
Yuen Zhou, Joel

Theory for molecular photonics

View profile for Zid, Brian
Zid, Brian

Gene Expression Control During Stress; mRNA Localization to Membrane-Less Compartments


Events and Seminars

04/29/2016 (Fri) at 11:00 AM
Inorganic Seminar
Professor David Tyler
Coordination Chemistry and Catalytic Reactions of H2 and N2 in Aqueous Solution; New Water-soluble Phosphines
05/02/2016 (Mon) at 11:00 AM
Organic Seminar
Professor Angel A. Martí
Searching for Biomolecules Using Light and Time: A Tale Told by Metals
05/04/2016 (Wed) at 01:00 PM
Thesis Defense
Don Duy Nguyen
Applications in Mass Spectrometry and Molecular Networking: The Pseudomonas Specialized Metabolome and Algae Biofuels
05/06/2016 (Fri) at 10:00 AM
Thesis Defense
Kristina Moriah Hamill
Overcoming Biological Barriers: Synthesis and Evaluation of Molecular Transporters
05/06/2016 (Fri) at 11:00 AM
Inorganic Seminar
Professor Michael Neidig
Structure, Bonding and Mechanism in Iron-Catalyzed Cross-Coupling
05/09/2016 (Mon) at 11:00 AM
Organic Seminar
Professor Zachary Ball
Designing enzyme-like catalysts: A rhodium(II) metallopeptide case study
05/13/2016 (Fri) at 11:00 AM
Inorganic Seminar
Professor Vince Lavallo
Ligand and Catalyst Design with Closo-Carborane Anions
More....