Cohen, Seth
Bioinorganic and coordination chemistry. Metalloprotein inhibitors and supramolecular materials.

Contact Information
Professor, Department of Chemistry and Biochemistry
Leslie Orgel Scholar in Inorganic Chemistry

Office: Pacific Hall 4100A
Phone: 858-822-5596
Email: scohen@ucsd.edu
Web: cohenlab.ucsd.edu
Group: View group members
Education
1998 Ph.D., University of California, Berkeley
1994 B.S/B.A, Stanford University
Awards and Academic Honors
2017
TREE Award, Research Corporation for Scientific Advancement
2016
Arthur C. Cope Scholar Award, American Chemical Society
2015
Leslie E. Orgel Faculty Scholar
2015
Fellow, American Chemical Society
2014
Fellow, Royal Society of Chemistry
2013
Fellow, American Association for the Advancement of Science
2008
Roger Revelle Fellow, American Association for the Advancement of Science
2006
CAREER Award, National Science Foundation
2004
Cottrell Scholar Award, Research Corporation for Scientific Advancement
2001
Chris and Warren Hellman Faculty Scholar Award
Research Interests
Metalloprotein Inhibitors - Bioinorganic/Medicinal Chemistry

Several metalloproteins are implicated in various diseases, including arthritis, heart disease, cancer, and others. Compounds containing ligands that chelate the catalytic metal ion in these proteins can act as effective inhibitors of potential therapeutic value. Our investigations focus on the design, synthesis, and evaluation of novel metalloprotein inhibitors based on new ligands for binding the active site metal ions.

Metal-Organic Frameworks - Inorganic/Materials Chemistry

We study the design, preparation, and properties of metal-organic frameworks (MOFs). MOFs are a fascinating new class of advanced materials that may be useful in a variety of technological applications. We use organic chemistry to modify the surface and interior of MOFs in order to tune and optimize their physical and chemical properties.

Primary Research Area
Inorganic Chemistry
Interdisciplinary interests
Materials
Synthesis
Biophysics

Outreach Activities
Mentor for the Alliance for Graduate Education and Professoriate (AGEP) students, University of California – Historically Black Colleges Initiative, Sloan Scholars Program, UCDC Science Policy Internship Program (SPIP)
Image Gallery




Selected Publications