Corbett, Kevin
Molecular mechanisms of recombination and chromosome segregation in meiosis and mitosis

Contact Information
Associate Professor, UCSD Dept. of Cellular and Molecular Medicine; Assistant Member, Ludwig Institute for Cancer Research

Office: CMM/E
Phone: 858-534-7267
2005 PhD, Molecular Cell Biology, University of California, Berkeley
2000 BS, Biochemistry, University of Virginia
Research Interests
Our laboratory is focused on the molecular mechanisms of chromosome segregation in mitosis and meiosis. We use biochemistry, X-ray crystallography, and cryo-electron microscopy to probe the structure, function, and interactions between proteins involved in meiotic chromosome pairing, crossover initiation and maturation, and chromosome segregation. We also collaborate with local labs on diverse projects, including CRISPR/Cas9 engineering and RNA targeting (with Gene Yeo), and on novel bacterial signaling pathways with potential roles in host-pathogen interactions (with Joe Pogliano and Victor Nizet).
Interdisciplinary interests
Macromolecular Structure
Cellular Biochemistry

Selected Publications