Siegel, Dionicio
Complex Molecule Synthesis
Complex Molecule Synthesis
Contact Information
Associate Professor, School of Pharmacy and Pharmaceutical Science
Office: Skaggs/Pharmaceutical Sci Bldg4272
Phone: 858-822-3666
Email: drsiegel@ucsd.edu
Web: profiles.ucsd.edu/dionicio.siegel
Office: Skaggs/Pharmaceutical Sci Bldg4272
Phone: 858-822-3666
Email: drsiegel@ucsd.edu
Web: profiles.ucsd.edu/dionicio.siegel
Education
2003 PhD, Chemistry, Harvard University
1997 BA, Chemistry, Reed College
2003 PhD, Chemistry, Harvard University
1997 BA, Chemistry, Reed College
Research Interests
The Siegel group is focused on complex molecule synthesis and the use of state of the art methods in organic synthesis to deliver new compounds with translational potential. The laboratory’s capabilities in developing efficient platforms to access rare, complex natural products leads into optimization and characterization of the compounds’ biological effects.
Interdisciplinary interests
Synthesis
Bioorganic
Bioorganic
Outreach Activities
To encourage diversity and careers in science, the Californian Shaman program provides high school students with research opportunities in multiple scientific disciplines and has been designed to afford lasting educational experiences that positively influence student professional development. Through a unique combination of hands-on laboratory experience and fieldwork, pre-college students engage in participant-directed projects that foster science self-efficacy and self-identification as scientists and provide the motivation and skills that enable students to have a careers in STEM discipline.
Image Gallery
Selected Publications
- Johnson TC,Chin MR,Han T,Shen JP,Rana T,Siegel D "Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion.", J Am Chem Soc, 2016, Vol. 138, Issue 18, 6068-73 [View]
- Camelio AM,Johnson TC,Siegel D "Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products.", J Am Chem Soc, 2015, Vol. 137, Issue 37, 11864-7 [View]
- Yuan C,Liang Y,Hernandez T,Berriochoa A,Houk KN,Siegel D "Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism.", Nature, 2013, Vol. 499, Issue 7457, 192-6 [View]