Zid, Brian
Gene Expression Control During Stress; mRNA Localization to Membrane-Less Compartments
Gene Expression Control During Stress; mRNA Localization to Membrane-Less Compartments
Contact Information
Assistant Professor of Chemistry and Biochemistry
Office: Urey Hall 5206
Phone: 858-822-6045
Email: zid@ucsd.edu
Web: zidlab.ucsd.edu
Group: View group members
Office: Urey Hall 5206
Phone: 858-822-6045
Email: zid@ucsd.edu
Web: zidlab.ucsd.edu
Group: View group members
Education
2008 PhD, Biology, Caltech
2000 BS, Chemistry, Truman State University
2008 PhD, Biology, Caltech
2000 BS, Chemistry, Truman State University
Appointments
2015 Assistant Professor, University of California, San Diego
2008 Postdoctoral Fellow, Harvard University
2015 Assistant Professor, University of California, San Diego
2008 Postdoctoral Fellow, Harvard University
Awards and Academic Honors
2011-2013
Derek C. Bok Award, Certificate of Distinction in Teaching
2011
American Cancer Society Postdoctoral Fellowship
2002
Glenn/AFAR Scholarship for Research in the Biology of Aging
Research Interests
Our group is interested in understanding fundamental properties of gene expression and their effects on the physiology of an organism. We are currently focused on how cells are able to coordinate transcription with translation through differential mRNA localization during stressful conditions. To tackle this problem we use an interdisciplinary approach combining basic biochemistry with next-generation sequencing, quantitative single-cell microscopy, and computational modeling.
Primary Research Area
Biochemistry
Biochemistry
Interdisciplinary interests
Cellular Biochemistry
Computational and Theoretical
Biophysics
Computational and Theoretical
Biophysics
Selected Publications
- Subramaniam AR, Zid BM, O'Shea EK, "An integrated approach reveals regulatory controls on bacterial translation elongation.", Cell, 2014, Vol. 159, Issue 5, 1200-11 [View]
- Zid BM, O'Shea EK, "Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast.", Nature, 2014, Vol. 514, Issue 7520, 117-21 [View]
- Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, Benzer S, Kapahi P, "4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila.", Cell, 2009, Vol. 139, Issue 1, 149-60 [View]